CoQ₁₀, or ubiquinone, is a lipid-soluble antioxidant which is found in every cell in the body. CoQ₁₀ is abundant in the mitochondrial membrane and plays an important role in the synthesis of adenosine triphosphate (ATP), a molecule of chemical energy upon which all cellular functions depend. The synthesis of ATP within the mitochondria is a multi-step series of biochemical reactions called the electron transport chain. As a coenzyme, CoQ₁₀ is required for several enzymatic reactions required to produce cellular energy and to protect the body against free radicals produced during this process. To maintain energy production, mitochondrial CoQ₁₀ is continuously recycled from ubiquinone, its ATP production state, to ubiquinol, its antioxidant, free radical scavenging state. CoQ₁₀, has been shown to extend cell life and benefit high-energy systems like the cardiovascular, neurological, and immune systems.

Suggested Use:

1 soft get capsule per day or as recommended by your health care professional.

CoQ₁₀ Depletion

The body’s ability to produce and metabolize CoQ₁₀ has been reported to decrease with age. CoQ₁₀ deficiency may be caused by insufficient dietary intake of CoQ₁₀, impairment in CoQ₁₀ production, drug-induced CoQ₁₀ depletion, gene mutations, and oxidative stress. HMG-CoA reductase is an enzyme required for the synthesis of cholesterol and CoQ₁₀. Cholesterol lowering medications inhibit this enzyme in order to reduce cholesterol synthesis but may also deplete CoQ10 status simultaneously. In the event of CoQ₁₀ depletion, supplementation can improve CoQ₁₀ status and help maintain optimal levels in the body. 

Antioxidant Protection

Oxidative stress is a condition that occurs when there is an imbalance of free radicals and antioxidants required to neutralize them, leading to oxidative damage. The extent of oxidative stress depends on the rate at which free radicals are generated, the level of antioxidant reserves, and the rate of repair of cellular and tissue damage that has occurred. This process has a significant impact on the body’s aging process. Ubiquinol is an electron donor because it has two hydroxyl groups. The electrons that ubiquinol donates help to neutralize free radicals thereby providing significant protection against toxic oxidative reactions in the body.

Cholesterol

CoQ₁₀ appears to be a preventive factor for reducing low-density lipoprotein (LDL) oxidation- a major factor for supporting healthy cholesterol levels. In a study examining the antioxidant effects of ubiquinol versus vitamin E, ubiquinol significantly reduced LDL lipid peroxidation more efficiently than vitamin E.